Full list of all 37 Marvel Heroes Omega achievements worth 1,030 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game.
The base game contains 35 achievements worth 1,000 Gamerscore, and there is 1 DLC pack containing 2 achievements worth 30 Gamerscore.
Prestige any Hero twice.
Complete the Cosmic Trial with any hero.
Loot 100 Artifacts.
Defeat 7 Different Super Villians in their Showdowns
Open 50 Bounty Chests in Operations
Prestige any Hero.
Get Five Heroes to Level 60.
Complete the Super Heroic Trial with any hero.
Defeat 150 Super Villains in Midtown Manhattan.
Complete 24 Different Special Events in Story Mode
Apply a Modification to an Artifact.
Complete 14 Different Operations
Defeat Loki in Chapter 9.
Visit Six Different Headquarters
Rescue 100 civilians in Midtown Patrol.
Loot a Cosmic Medallion
Defeat Doctor Doom in Chapter 8.
Defeat Mister Sinister in Chapter 7.
Level any vendor to level 10.
Collect any 100 Relics of the same type
Reach level 60 with any hero.
Defeat Magneto in Chapter 6.
Defeat Juggernaut in Chapter 5.
Defeat The Kingpin in Chapter 4.
Find and Defeat a Cosmic Doop
Defeat a Training Room Target Dummy.
Defeat Elektra in Chapter 3.
Defeat The Hood in Chapter 2.
Defeat Doctor Octopus in Chapter 1
Defeat Green Goblin in the Prologue
Loot 1,000,000 Credits.
Explore all of the Treasure Rooms in each chapter of Story Missions.
Complete 25 Legendary Quests.
Fully upgrade a Legendary Item.
Earned all other Marvel Heroes Omega achievements.
Defeat 10 different members of the Sinister Six.
Alone, defeat Shocker in under 50 seconds upon entering the Abandoned Subway Operation.