Full list of all 37 Marvel Heroes Omega achievements worth 1,030 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game.
The base game contains 35 achievements worth 1,000 Gamerscore, and there is 1 DLC pack containing 2 achievements worth 30 Gamerscore.
Complete 25 Legendary Quests.
Rescue 100 civilians in Midtown Patrol.
Complete the Super Heroic Trial with any hero.
Level any vendor to level 10.
Reach level 60 with any hero.
Complete 14 Different Operations
Defeat a Training Room Target Dummy.
Visit Six Different Headquarters
Defeat Loki in Chapter 9.
Explore all of the Treasure Rooms in each chapter of Story Missions.
Defeat Doctor Doom in Chapter 8.
Complete 24 Different Special Events in Story Mode
Defeat Mister Sinister in Chapter 7.
Defeat Magneto in Chapter 6.
Defeat 7 Different Super Villians in their Showdowns
Defeat Juggernaut in Chapter 5.
Defeat The Kingpin in Chapter 4.
Defeat Elektra in Chapter 3.
Defeat The Hood in Chapter 2.
Defeat Doctor Octopus in Chapter 1
Defeat Green Goblin in the Prologue
Loot 1,000,000 Credits.
Find and Defeat a Cosmic Doop
Collect any 100 Relics of the same type
Loot 100 Artifacts.
Apply a Modification to an Artifact.
Open 50 Bounty Chests in Operations
Fully upgrade a Legendary Item.
Defeat 150 Super Villains in Midtown Manhattan.
Loot a Cosmic Medallion
Prestige any Hero.
Complete the Cosmic Trial with any hero.
Prestige any Hero twice.
Get Five Heroes to Level 60.
Earned all other Marvel Heroes Omega achievements.
Defeat 10 different members of the Sinister Six.
Alone, defeat Shocker in under 50 seconds upon entering the Abandoned Subway Operation.