Full list of all 37 Marvel Heroes Omega achievements worth 1,030 gamerscore. It takes around 80-100 hours to unlock all of the achievements in the base game.
The base game contains 35 achievements worth 1,000 Gamerscore, and there is 1 DLC pack containing 2 achievements worth 30 Gamerscore.
Prestige any Hero twice.
Fully upgrade a Legendary Item.
Get Five Heroes to Level 60.
Loot 1,000,000 Credits.
Prestige any Hero.
Loot 100 Artifacts.
Open 50 Bounty Chests in Operations
Loot a Cosmic Medallion
Collect any 100 Relics of the same type
Complete 25 Legendary Quests.
Complete the Cosmic Trial with any hero.
Apply a Modification to an Artifact.
Defeat 150 Super Villains in Midtown Manhattan.
Complete the Super Heroic Trial with any hero.
Explore all of the Treasure Rooms in each chapter of Story Missions.
Reach level 60 with any hero.
Complete 14 Different Operations
Defeat Loki in Chapter 9.
Visit Six Different Headquarters
Defeat Doctor Doom in Chapter 8.
Complete 24 Different Special Events in Story Mode
Level any vendor to level 10.
Rescue 100 civilians in Midtown Patrol.
Defeat Mister Sinister in Chapter 7.
Defeat a Training Room Target Dummy.
Defeat Magneto in Chapter 6.
Defeat 7 Different Super Villians in their Showdowns
Find and Defeat a Cosmic Doop
Defeat Juggernaut in Chapter 5.
Defeat The Kingpin in Chapter 4.
Defeat Elektra in Chapter 3.
Defeat The Hood in Chapter 2.
Defeat Doctor Octopus in Chapter 1
Defeat Green Goblin in the Prologue
Earned all other Marvel Heroes Omega achievements.
Defeat 10 different members of the Sinister Six.
Alone, defeat Shocker in under 50 seconds upon entering the Abandoned Subway Operation.