Full list of all 62 Mass Effect 2 achievements worth 1,355 gamerscore. It takes around 50-60 hours to unlock all of the achievements in the base game.
The base game contains 50 achievements worth 1,000 Gamerscore, and there are 5 DLC packs containing 12 achievements worth 355 Gamerscore.
Defend a human colony from attack
Kill enemies with 5 different heavy weapons during the game
Successfully recruit the krogan
Incinerate the armor of 25 enemies
Successfully recruit the biotic Convict
Complete 5 missions discovered by scanning unexplored worlds
Evolve any power
Successfully recruit Archangel
Obtain 10 technology upgrades
Complete any research project in the Normandy's laboratory
Successfully recruit the Professor
Make 20 enemies scream as they fall or are set on fire
Perform 30 headshot kills with any weapon on humanoid targets
Unlock 15 new Mass Effect 2 codex entries
Visit 100% of the planets in an unexplored cluster
Complete a mission discovered by scanning an unexplored world
Retrieve mineral resources by scanning and probing a planet in the galaxy map
View all advanced combat training videos at Shepard's private terminal.
Disrupt the shields of 25 enemies
Return to active duty
Personalize your armor in your quarters on the Normandy
Save your crew from an overwhelming attack
Successfully recruit the quarian
Successfully recruit the Justicar
Successfully recruit the Assassin
Obtain geth technology
Gain the loyalty of the Cerberus Officer
Gain the loyalty of the Cerberus Operative
Gain the loyalty of the biotic Convict
Gain the loyalty of the krogan
Gain the loyalty of Archangel
Gain the loyalty of the Professor
Gain the loyalty of the quarian
Help the Justicar resolve her mission
Gain the loyalty of the Assassin
Hack a geth collective
Complete the investigation of a derelict alien vessel
Use the Omega 4 Relay
Save humanity throughout the galaxy from certain annihilation
Survive suicide mission
Complete the game on the "Insanity" difficulty level without changing the setting
Keep your team alive through the suicide mission
Complete Mass Effect 2 twice, or complete it once with a character imported from Mass Effect 1
Successfully pursue a relationship with a teammate
Shoot and kill 20 enemies while they're knocked back by a punch
Thresher Maw defeated
Hit 20 different targets with multiple biotic powers to combine the effects
Warp the barriers of 25 enemies
Reach Level 30 with one character
Fully upgrade a weapon
Gain the loyalty of the thief
Collect 6 Cerberus data packets scattered across Aite
Successfully shut down the rogue VI in Project Overlord
Use all information terminals in the Shadow Broker’s stronghold
Defeat the Shadow Broker’s Assassin
Confront the Shadow Broker
Complete the Shadow Broker Mission pack on Hardcore or Insanity
Reminisce with Liara on the Normandy
Gain the loyalty of the mercenary
Complete the Arrival DLC pack
Survive all five waves in the battle for Object Rho
Rescue Dr. Amanda Kenson without attracting hostile attention