Full list of all 40 Prototype achievements worth 1,000 gamerscore. It takes around 35-40 hours to unlock all of the achievements on Xbox 360.
You've completed Story Mode on hard difficulty.
You've killed 53,596 infected.
You've achieved a Platinum Medal for all Events.
You've collected all Landmark collectibles scattered across New York City.
You've acquired all nodes in the Web of Intrigue.
You've collected all Hint Collectibles scattered across New York City.
You've completed Story Mode without a single death.
You've discovered what happened to Alex Mercer.
You've consumed fewer than 10 Civilians during Story Mode.
You've completed 3 missions without causing a single Military Alert.
You've discovered the truth behind Hope, Idaho.
You've discovered the history of Elizabeth Greene.
You've achieved a rating of Gold or better in all Events.
You've completed all Consume Events.
You've acquired all upgrades available.
You've infiltrated 10 Military Bases disguised as a Commander.
You've destroyed 20 Helicopters in a single Helicopter flight.
You've shot down 50 helicopters while driving armor.
You've destroyed 2,000 vehicles.
You've completed the Supreme Hybrid Boss Battle.
You've completed the Mother Boss Battle.
You've caught an object tossed by a Hydra; and have thrown it back.
You've evaded 10 strike teams.
You've completed the Supreme Hunter Boss Battle.
You've destroyed 10 Military Bases or Infected Hives in New York City.
You've consumed 200 characters to regain health.
You've consumed 50 Web Targets.
You've brought down your wrath on 25 strike teams, erasing them from existence.
It's definitely not you. You've patsied 5 military personnel.
You've seized 50 vehicles from enemy hands.
You've destroyed 25 Infected Water Towers before they hatched.
You're now certified to drive and fly all vehicles.
You've completed a mission without causing a single Military Alert.
You've completed the Specialist Boss Fight.
You've killed 15 characters with a single Whipfist attack.
You've run over 500 characters in a single tank.
You've completed the Hunter Boss Encounter.
You've used the Upgrade Menu to acquire an Upgrade.
Web of Intrigue unlocked.
You've killed 50 characters in 5 seconds.