Full list of all 138 Ring of Pain achievements worth 1,555 gamerscore. It takes around 60-80 hours to unlock all of the achievements in the base game.
The base game contains 99 achievements worth 1,000 Gamerscore, and there are 3 DLC packs containing 39 achievements worth 555 Gamerscore.
Accept 100 items from Owl
Have 100+ max Health
Freeze 200 creatures
Stealth past 10 Banefangs
Complete the Dark Ending
Kill 10 creatures with reflect damage
Play the game for 10 hours
Poison 10 Banefangs
Poison 300 creatures
Die to a gravestone
Complete the Light Ending
Teleport or knockback an explosive creature 50 times
Deal 99+ damage in a single attack
Kill 1000 creatures
Successfully Stealth past 100 different creatures
Die 25 times
Spend 100+ Souls with Soul Spill
Die to a boss
Have 500+ Souls
Reach the boss on maximum health
Choose your final path
Attack Owl friend
Freeze 50 creatures
Reach a depth of 12
Kill 20 different types of creatures in a single game
Kill multiple creatures in a single turn 50 times
Parry 50 creatures
Poison 50 creatures
Go from full Health to 1 Health in a single turn
Make a wish
Get cursed by potions 3 consecutive times
Die within 30 seconds of starting a run
Kill 20 Scroungers
Successfully Stealth past 10 different creatures in a single game
Shuffle 10+ times in a single run
Have a full inventory
Transform 20 creatures
Die with Rainbow Socks equipped
Use a Shrine
Kill a Bilebag from a distance
Discover 10 new paths
Kill 100 creatures
Deal 25+ damage in a single attack
Kill a Pupper
Kill a cute, harmless frog
Reach a depth of 6
Exit a room without attacking any creatures
Discover a new path
Complete the Tutorial
Killed by equipping items
Have 60+ Clarity
Have 60+ Speed
Die 250 times
Have 60+ Attack
Have 60+ Defense
Kill a Wretched Amalgam that has 50+ max health
Have 5 creatures explode in one turn
Pacify 25 Hounds
Reach Depth 6 without attacking a creature
Play 7 Daily Dungeons
Reach depth 6 without drinking any potions
Equip 8 different Head slot items in one playthrough
Dig up an item in the Graveyard
Kill a Shrieker
Reduce your max health to 1 with the Fountain of Life
Complete a run in under 18 minutes
Reach Depth 12 on Hard difficulty
Defeat the Owl on Hard difficulty
Die in Hard Mode
Get a score of over 9000 in a Daily Dungeon
Complete a Daily Dungeon
Reach Depth 12 having killed all creatures on the way
Complete a run without any Epic or Legendary items equipped
Unlock 70 Achievements
Reach the boss with less than 20% health remaining
Complete a run 5 times
Complete a run after travelling down a deep pit
Kill a Stone Shifter in Hard Mode
Complete a run with the Spoon
Fully upgrade the Spoon
Kill 10,000 creatures
Kill 3 Fire Breeds with an explosion
Complete a run without using any Scrolls or Spellbooks
Intimidate 250 creatures
Have 20 Poison on yourself
Heal 50+ with one potion
Kill Sam and spare the companions
Complete a run without replacing any equipped items
Kill 10+ creatures in one turn
Complete a run without using any rerolls
Hex a frog
Complete a run without ever equipping a Rare or Epic item
Complete a run without ever equipping an Epic or Legendary item
Complete a run with Inverted Candle
Complete a run with 4 or fewer items equipped
Complete the Light Ending on Hard difficulty
Complete the Dark Ending on Medium difficulty
Complete the Light Ending on Medium difficulty
Kill an Ancient Ice Beast which has more than 30 Defense
Get Poisoned twice in one turn
Complete a run without discarding any items
Petrify 50 creatures
Complete a run with 5 or less max Health
Complete a run with 0 or less Defense
Complete a run with 0 or less Attack
Have 2000+ Souls
Complete a run without ever equipping a Common item
Hit Owl with a spoon
Get hit by 20 explosions in one run
Kill a Spineback while its spines are exposed
Destroy 20 equipped items in one run
Transform a Firebead that was about to self-destruct
Reach depth 10 without hurting a Gnawling
Complete a run without ever equipping any Body, Head, Arms, Legs or Feet items
Kill all enemies in a dungeon with the rock
Escape fatal poison damage by leaving dungeon
Use 35 Exit cards of any type in a single run
Get cursed while at 1 health
Complete a run without entering any special dungeons (only use the black exits)
Reroll 30 times in a single run
Complete a run with the first item equipped
Reach Depth 12 on Medium difficulty
Survive a total of 60+ damage in a single Nest or Swamp dungeon
Complete a run without killing a Scrounger
Wear items of the same set in the Head, Body, Legs, and Feet slots
Kill a boss without any items equipped
Kill all creatures in a core path dungeon on the first turn
Kill a creature with exactly the same stats as you
Complete a run without taking any explode damage
Complete a run without gaining any stats from Stat Boosts
Spend more than 200 Souls rerolling a chest and then discard it
Kill a boss without ever attacking them directly
Complete a run with your Stealth, Crit and Dodge chance lower than 10%
Complete a run with only Multiclass items equipped
Complete a run with only Brute items equipped
Complete a run with only Stalker items equipped
Complete a run with only Diviner items equipped
Complete a run with only Soul Kin items equipped