Full list of all 49 Star Trek achievements worth 1,000 gamerscore. It takes around 20-25 hours to unlock all of the achievements on Xbox 360.
Killed 3 enemies while in a single downed state
Completed half of all Optional Objectives
Connected every weapon's alternate fire with enemies
Killed 50 enemies with the Arc Driver
Killed 50 enemies with the Pillager
Ordered your teammate (AI or co-op player) and had him complete 5 bypasses in a row
Killed 50 enemies with the Marauder
Performed Mind Meld on 10 different enemies
Killed 50 enemies with the Vulcan Pulse Cannon
Completed the Space Battle with a hull integrity of 85% or more
Completed the game on hard difficulty setting
Bought all upgrades for the Captain's Phaser
Killed 50 enemies with the Starfleet Phaser Rifle
Revived your teammate (AI or co-op player) 20 times
Killed 100 enemies with the Captain's Phaser
Killed 20 enemies with Plasma Grenades
Killed 3 enemies while your teammate (AI or co-op player) was in a downed state
As Kirk, had a Gorn enemy melee you
Found all research items
Killed 50 enemies with the Railer
Killed 50 enemies with the Ravager
Found all audio logs
As Spock, bled out during a downed state, leaving Kirk alone and failing the mission
Killed 20 enemies with the Striker
Completed all Optional Objectives
Bought all upgrades for the Vulcan Repeater
Bought all upgrades for the Tricorder
Completed the game on any difficulty setting
Completed the Mothership chapter on any difficulty
Completed all chapters in co-operative play
Completed the Enterprise Capture chapter on any difficulty
Took down 30 enemies in a non-lethal manner
Found half of all audio logs
After the brawl, escaped in less than 6 minutes in "The Trials" chapter
Completed the Gorn Planet & The Trials chapters on any difficulty
Won the brawl against your buddy in "The Trials" chapter
Killed 20 enemies with the Starfleet Type III Rifle
Cleared 30 mini-games including co-operative hacks, bypasses, and power reroutes
Found half of all research items
Killed 100 enemies with the Vulcan Repeater
Completed the Volatile Cargo & Flashback chapters on any difficulty
Completed the Frontier Starbase chapter on any difficulty
Hacked an enemy drone to your side and have it kill another enemy
Completed the Space Battle chapter on any difficulty
Completed four chapters in co-operative play
Completed the New Vulcan chapter on any difficulty
Killed or took down an enemy that your teammate (AI or co-op player) has stunned
Completed one chapter in co-operative play
Completed the Helios-1 chapter on any difficulty