Full list of all 79 The Binding of Isaac: Rebirth achievements worth 1,520 gamerscore.
The base game contains 58 achievements worth 1,000 Gamerscore, and there are 3 DLC packs containing 21 achievements worth 520 Gamerscore.
Kill Satan with ???.
Beat the Caves/Catacombs without taking damage.
Kill Satan with Eden.
Kill Satan with Maggy.
Kill Isaac with Azazel.
Kill Satan with Eve.
Kill Isaac with Eve.
Kill Isaac with Lazarus.
Kill Isaac with Judas.
Beat the Basement 40 times.
Beat the Womb/Utero without taking damage.
Beat the Caves 30 times.
Beat the Dark Room with Isaac.
Beat the Chest or Dark Room without taking damage.
Beat the Chest.
You are the best!
Kill Isaac with Samson.
Beat Cathedral 5 times.
Kill Isaac with Maggy.
Kill Isaac with Eden.
Kill Isaac with Cain.
Kill Mom using the Bible.
Kill Isaac with Isaac.
Kill Mom's Heart 11 times.
Beat the Dark Room.
Kill Mom's Heart 10 times.
Kill Mom's Heart 9 times.
Beat the Depths 20 times.
Kill Mom's Heart 8 times.
Kill all 7 sins.
Kill Satan with Samson.
Beat Sheol 5 times.
Kill Satan with Azazel.
Kill Mom's Heart 5 times.
Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment, or Speed Ball.
Beat 2 levels in a row without picking up any hearts.
Kill Satan with Judas.
Beat 2 levels in a row without taking damage.
Beat the Basement/Cellar without taking damage.
Kill Mom's Heart 3 times.
Kill Satan with Cain.
Kill Satan
Kill Satan with Isaac.
Beat the Womb for the first time,
Beat the Boss Rush.
Hold 55 or more pennies at one time.
Kill Mom.
Have 4 or more soul hearts at one time
Make 3 deals with the devil in one run.
Have 7 or more max red hearts at one time.
Finish the game's final secret.
Kill Isaac with The Lost.
Kill Satan with The Lost.
Kill Satan with Lazarus.
Beat the Depths/Necropolis without taking damage.
Beat all 20 Challenges.
Collect all items and unlock all secrets and endings.
100% the game!
Kill The Lamb with Keeper
Kill ??? with Keeper
Donate 1000 coins in Greed Mode
Kill The Lamb with Lilith
Kill ??? with Lilith
Beat Greed Mode with Azazel
Collect all items and unlock all secrets
Complete ??? 3 times.
Beat Hard mode as Lazarus without losing a life
You are just like your father...
The other side is calling...
Beat everything in Hard Mode as every character.
...
RIP
Unlocked a new area
Beat Delirium
Just Stop!
Kill Mega Satan
Donate 500 coins to the Greed Machine
Kill The Lamb
Uncover some lost remains..