Here is the full list of all 28 Vampyr achievements worth 1,000 gamerscore. It takes around 40-50 hours to unlock all of the achievements on Xbox One.
Complete the game
Defeat the Disaster
Take care of Swansea's fate
Defeat McCullum
Upgrade a weapon to level 5
Take care of Aloysius's fate
Defeat Doris
Defeat Mary
Take care of Sean's fate
Defeat Fergal
Heal 10 citizens
Take care of Dorothy's fate
Eat 10 rats
Let Clay live during your first meeting with him
Take a ride with Doctor Swansea
Upgrade a weapon with a module
Upgrade a weapon
Go to the Shelter and rest…
Embrace Clay during your first meeting with him
Save this poor plant with water
Find all Melee Weapon
Find all ranged weapons
Find all Off Hand Weapon
Find the recollection of Paulus Aurelianus
Gather all collectibles
Turn a district to hostile status
Finish the game without killing any citizens (not unlockable in Story Mode)
Turn all districts to hostile status