This is related to the side quest called A Good Defense
(available after finding "Home Safe Tests" document in Maintenance sector NSC Energy Converters computer room).
The actual quest is located in the Training Course. First, you need to complete a timed obstacle course - you need to shoot targets and fling energy cubes to the receptables to proceed to the next rooms. You have to be quick, though.
Once you are on the other side of the blast door in the actual chamber with the Safe, you need to break the barrier with launched objects (will need several). Cleanse the Safe, and complete the Astral Plane challenge, which is a relatively trivial task of just moving forward and deflecting the enemy fire with your new