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"Wise fwom your gwave!"
This is a very simple achievement.
You must make sure you kill pretty much every enemy you see. Especially the 2 headed blue wolves. These drop the orbs that increase your power and eventually turn you into a creature.
Kill everything you see and, once you get to the boss (you should be the wolf by now) simply kill him to earn enough points.
The boss is fairly simple he'll just stand there and throw heads at you. Keep firing at him and either avoid the heads or use the dash attack to destroy them.
Once dead you should have earnt over 100,000 points and the achievement will unlock.
The video below is the first level showing how easy it is to gain enough points. Video was uploaded by "Jiblet101".