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Upgrade all Runes

2 guidesOffline Game Mode - These achievements require play in game modes that do not necessitate a connection to any online services.Single Player - These achievements can be obtained by a single player.Collectable - These achievements are obtained by exploring the game environment to find a set of unique objects.
20 May 2016 21 May 2016
56 1 8
Each Rune has a specific task that needs to be completed (i.e.: Ammo Boost - Pick up 500 weapon items). If you are following a guide and have all of the Runes up to and including Mission 7 (Argent Facility Destroyed) you can restart a check point to clear all of the runes and a few of the Masteries. The 7th Rune prior to this point is In-flight Mobility.

You will reach a checkpoint that will have a Gauss Cannon and a Datalog directly in front of you after going through a door. There will also be a Hologram in the same room on the left wall. In this area there is a Gore Nest, about 5 possessed, a 'flaming' possessed (Cannot recall the name), a Hell Razer, and a Shielded Security possessed. Pick up the Gauss (if you didn't already have it), snipe the Hell Razer coming down the steps in the back, and then snipe the Security Possessed either just before or after he jumps down from the lest side so he won't have his shield up, then it's easy pickings on the fodder. Clear the room - even the 3 on the opposite side if you really want to, then either restart the check point or jump onto the purple electric floor to kill yourself. Be sure to not active the Gore Nest until after you have everything upgraded so you do not lose the checkpoint.

In this area I finished all of my current Runes except for Ammo Boost; I also mastered the Pistol, Super Shotgun, and Gauss Cannon Siege Mode. This spot clears the hardest ones imo as there are 3 that deal with Glory Kills and the Possessed are easy targets. After this the rest of the runes are easy to clear - only exception being the final Rune Saving Throw. I have only just gotten to this on and obtaining it is challenging. You get 1 health point and a Gauss Cannon in Siege mode to clear 9 demons.

EDIT: The Saving Throw is easily upgraded as well. After you acquire it and you continue on in the mission (Lazarus), you will follow a walkway and drop into a circular room. A door will open to a hallway with a portal at the end which will put you into a battle with a bunch of demons. With Saving Throw active you basically just need to let them 'almost' kill you. Just before you would die everything will go slow motion then blast with the BFG and wipe out the demons; then just rinse and repeat. Kill 10 of them in that slow mode and it will upgrade. If you get hit during the slow mode you will die and have to try again. Be sure to restart your check point after the upgrade you so get all of your ammo back, as after that battle you go against the 2-phase Cyber-Demon fight! So be sure to abuse the Riches rune to kill off everything while not spending ammo.

Hope this helps!
DrelzarI know its easy to just use equipment, but I found out a glitch where if you press the equipment button to use the hologram and then press the weapon wheel button like you were switching back to your last held weapon it will cancel the use of it but still count towards the rune. In this way you can get that rune up in 30 seconds give or take.
Posted by Drelzar on 30 May 16 at 07:48
Shadow XBLA good trick for the ammo pickup Rune is to use the chainsaw, which spits out tons of ammo. Then use some of each, and do it on another demon.
Posted by Shadow XBL on 13 Jul 16 at 16:53
xl Minnesota lx@NoHeroes94 I'm having the same issue as well. Did the the first playthrough and now none of my acheivements are unlocking including the multiplayer ones
Posted by xl Minnesota lx on 16 Jul 16 at 21:25
NoHeroes94@xl Minnesota lx they unlocked 4 days later. Worst. Joke. EVER Bethesda

So random by relieved haha. But Yeh I had massive issues where no achievements would unlock for DOOM
Posted by NoHeroes94 on 19 Jul 16 at 17:16
The SCHWARTZ 00Shadow XBL, brilliant suggestion with the chainsaw. I farmed this section mentioned in the OP and got my 500 refills within 30 minutes.
Posted by The SCHWARTZ 00 on 05 Sep 16 at 05:13
Sergeant FuryI just discovered that the Equipment power rune is super easy. At the part where you
*** Spoiler - click to reveal ***

all you have to do is mash the equipment button. There is no cooldown here, so it can be completed in 10 seconds or so.
Posted by Sergeant Fury on 14 Sep 16 at 01:04
netstrykerI did it naturally during the campaign.
Posted by netstryker on 26 Oct 18 at 02:40
OnsidicA note for saving grace, when i dropped down in the final area, i was doing weapon challenges. (head shot hell knight with guass cannon). I got low health and screen went shaky, i still had siege weapon on by accident. When i fired it killed 3 demons at the same time. My challenges went from 1/10 to 4/10 so looks like any instant kills in that moment count.
Posted by Onsidic on 24 Mar 19 at 01:56