Upon starting the level, move forward, and you will see a smuggler tied up in front of a wall very gruesomely. Take the path to his right to find your first Gene Bank. Gene Banks become very useful late in the game, because they allow you to change your setups of equipped Plasmids and tonics. You'll probably notice that there are a lot of locked slots at the moment, but as we progress through the game, we will be able to buy slots and equip more Plasmids and tonics at any one time. Choose which setup you want at the moment (I would recommend switch Telekinesis for Electro Bolt or Incinerate), and proceed through the pathway past the Big Daddy corpse and through the door.
After proceeding through the next few hallways, you will emerge into a very large room, and you'll see a Big Daddy and a Little Sister ahead of you. Kill the Big Daddy with whatever weapon you see fit, and then deal with the Little Sister. Save her with . Now, since this is your third saved Little Sister, Tenenbaum wants to reward you with a gift, and next time you reach a Gatherer's Garden, you will notice a surprise present of 200 ADAM. This will happen for every three Little Sisters you save.
Jump down onto the wharf in front of you, and you will notice Tonic #8/53: Medical Expert. in one of the mounds of sludge in front of you. This tonic will make first aid kits give you slightly more health. While collecting this tonic, you will be getting shot by the turrets at either end of the wharf, so try to absorb as many hits as you can. Turn around and hack the turret closest to you. Now, turn around again, kill the splicers in front of you, and crouch under the walkway to your right. Hack the turret at this end when you are close enough, and behind the turret is Audio Diary #20/122: Bathysphere Keys.
Now head up the walkway and through the door, killing splicers as you go, until you reach another Gene Bank. A rocket turret will be shooting at you from across the room, so I would recommend hacking that before doing anything else in this large area. If you head back to the where the Gene Bank was, you'll notice a Gatherer's Garden on your way. In front of the Gatherer's Garden will be a teddy bear that includes 200 ADAM, some pistol rounds, and a new Plasmid, Hypnotize Big Daddy. This Plasmid will make Big Daddies your personal bodyguards for a short time. Interact with the Gatherer's Garden and buy the Plasmid Slot. This will unlock:
I also bought the second slot that becomes available, and I would recommend making the slots your top priority when at Gatherer's Gardens. If you have the free DLC installed, you can also buy your 5 free tonics and free Plasmid for 1 ADAM each now. These DO count towards the 53 tonics achievement, but in case you don't have the DLC or are playing the JP or KR regional variants, I will list all 53 tonics in this guide. At this Gatherer's Garden, I would also recommend buying the Plasmid, Winter Blast, which freezes enemies in place. Also buy Tonic #9/53: Extra Nutrition. This tonic gives you slightly more health when picking up snacks or bandages.
Now, from where the rocket turret was, head down the stairs and into the water. Follow this watery pathway all the way to the end, and you will find a gate with a keypad lock next to it. The code is 5380. Inside, you will find an electrocuted body, some loot, and Audio Diary #21/122: Timmy H. Interrogation. Turn around, and enjoy the jump scare by another splicer. Once you get back up the stairs, head behind the rocket turret now, and head through the door. Knock on the Fontaine Fisheries door in front of you, and Peach Wilkins will give you a monologue.
A spider splicer will now jump from the ceiling, so do your best to kill it (This spider splicer has way more health than normal spider splicers). He will escape after taking enough damage. Head out the door after some more monologue, and follow the arrow into the next hallway until you are attacked by a large number of splicers. Kill all of them, and use the large metal grate sticking out of the ground as a guide for the next audio diary. While staring at the grate from where you first entered the hallway, look right, and head into the small room immediately on your right. Drop down into the hole and follow it all the way to the end. You will find Audio Diary #22/122: Fontaine Must Go buried in the sludge.
Follow the arrow now into another large room. You should see a Big Daddy walking around as soon as you walk in. Kill him in whichever manner you please, and then deal with the Little Sister. Save her with . There will also be a lot of splicers in this room to kill and a rocket turret to hack. There are also three audio diaries to find in this large room before destroying the lock. Basing your position off of where you entered the room, head forward, going around the boxes, and you will find Audio Diary #23/122: Finding The Sea Slug on a table in front of you. Now turn left, and you will enter the central section of this room. Turn left here to see Audio Diary #24/122: Masha Come Home up against the Gatherer vent. Turn around and head into the room on your left now to find a corpse on the ground. Search the body to find Audio Diary #25/122: Picked up Timmy H. Destroy the lock in front of you now, kill the splicer, and take a left to find Audio Diary #26/122: Watch Fontaine sitting on a wooden panel in front of the vending machine.
Hack the security cameras and follow the arrow to a locked gate. Destroy the lock, and hack every mechanical device in this serpentine room. Once you have done so, head toward the far end of the room, and you will see an open gate in front of you. Turn left from this gate, and you will see a small vent on the left wall. Crawl into this vent, and follow it to the end. Hack the security camera, and on the desk at the end of the room is Audio Diary #27/122: Have My Badge. You will also now find the Grenade Launcher, which is one of my least used weapons in the game, since it carries almost no ammo, and nearly every other weapon has explosive ammunition. You can also hack the safe in this room. Now you can head through the aforementioned gate and through the hole in the wall. Head through this hallway and the door, and you will find the Camera on the table. Now, you are going to want to murder this Camera by the end of the game, and let me tell you why:
With the Camera, you will do research, and research will allow you to access new tonics, receive damage bonuses on specific splicers, and obtain a large percentage of this game's achievements. The way you do research is by taking photos of splicers, and better photos will give you larger research bonuses. For example, an action shot, a shot with multiple enemies, and a first-time shot of that specific splicer will grant you more research points. You are going to have to take a LOT of photos to maximize your research, and if you're taking photos at every possible opportunity, you probably still won't have every subject fully researched until Olympus Heights. Taking photos requires film, so buy those from hacked vending machines whenever you are running low so that you can take pictures of every enemy you see. Take a photo of every enemy from here on out. The categories of enemies that you will need to take photos of are:
- Thuggish Splicer (Melee Splicer)
- Leadhead Splicer (Gun Splicer)
- Nitro Splicer (Explosive Splicer)
- Spider Splicer (Wall-crawling Splicer)
- Houdini Splicer (Teleporting Splicer)
- Rosie (Big Daddy with Rivet Gun)
- Bouncer (Big Daddy with Drill)
- Little Sister
- Turret (Any kind)
- Security Bot
- Security Camera
Like I said, you will receive tonics for research, but I will list them at the points in the game in which I receive them to give you a more accurate count of your tonics when checking your numbers at a Gene Bank. You may unlock these tonics earlier or later than I do, but as long as you reach max research, you will receive all of them before the final boss.
For taking your first photo and receiving an A rank, you will unlock:
As you reach the maximum research rank for all different categories of enemies, you will unlock the following throughout the game:
I will also point out the locations in which I unlock these achievements as I progress through the walkthrough. Once again, these may happen earlier or later for you.
Now that you're in possession of the camera, do your best to take an A Rank photo of the Spider Splicer in the room adjacent to you. If you do so, you will unlock:
For all subjects, keep taking photos until the game doesn't let you. By taking photos of every enemy, you should leave yourself with a lot of leeway with hitting max research across all subjects. Head out of the room now, kill the splicer, and before dropping off of the balcony from the now open window, pick up a new Plasmid on said balcony. It is Security Bullseye, which forces security bots and turrets to attack whichever enemy you throw your Plasmid on. Drop down from the balcony now, killing the splicer and hacking the security camera. Turn around from the vending machine, and you will see Audio Diary #28/122: Adam Discovery in a crate. Turn left from the diary, head through the door, and directly in front of you next to the burning pipes is Audio Diary #29/122: Eden Leaking.
Be cautious when entering the next hallway, because there will be a security camera on the right. Hack it, kill the splicers, and on the bench below the security camera, you will find Audio Diary #30/122: Fontaine's Smugglers. While researching the enemies in this corridor, I also unlocked Leadhead Splicer Research Level 2, which unlocks Tonic #10/53: Scrounger. This is one of the most useful tonics in the game, as it lets you do double searches of any lootable object. If you find loot, there's no need to use the tonic, but if you find nothing, this tonic is incredibly helpful. Have it equipped at all times. At the end of this hallway, take the left path to enter the Fighting McDonagh's Tavern.
You will notice a Spider Splicer jump in front of you and out of your line of sight when entering the tavern. Take a left, hack the vending machine, and fill your camera with film. Kill the splicers here and enter the water on the right side of the room (on the Gene Bank's side). Enter the vent, and turn around as soon as you enter it to find Audio Diary #31/122: Meeting Ryan. If you follow this vent to the end, you can break open the other side to create a sequence break, but that's highly unnecessary when we have collectible hunting to do. Head back to the entrance of the tavern, and head through the main door. Upon entering the room, there will be some splicers to kill. I also unlocked Leadhead Splicer Research Level 4 at this point, which unlocks Tonic #11/53: Electric Discharge 2. This works just like the first tonic of its kind, but if both are equipped, their effects stack, and you do a ton of damage when struck. Keep both equipped if possible.
From where you entered, if you look directly in front of you, you will find Audio Diary #32/122: Smuggling Ring on the circular table (Well, circle on a barrel). Head forward from this, and you will find Audio Diary #33/122: Working Late Again on another "table" on the left side of the tavern. Now, jump behind the bar in the center, and use Electro Bolt on the door switch so that you can enter. Head into the next door ahead of you, and you will find Audio Diary #34/122: Rapture Changing on the desk at the far end of the room. Now leave this room and head back to the bar. Head to the left of the bar and into the bathroom to kill the Nitro Splicer, and then head upstairs to kill all of the enemies in this area. The next Spider Splicer will be close by, but first, let's finish up some collectibles.
From where you walked up the stairs, take a left, and you will see another door with an Electro Bolt lock to your left. Use Electro Bolt on it. Once inside, there will be a Leadhead Splicer waiting for you behind the bed, and at this point, I unlocked:
Kill him, and at the foot of the bed where there is something very kinky and interesting going on, you will find Audio Diary #35/122: Arresting Fontaine. Head out of the room now, and the first door on your left will have another keypad lock. The code is 7533. Head to the back of the room, and on the mattress, you will find Audio Diary #36/122: Saw Masha Today. Attack the poster of Jasmine Jolene now with any weapon, and you will find Tonic #12/53: Shorten Alarms. This tonic reduces the duration of security camera alarms and is very useful when trying to research the security cameras. That being said, I would recommend at least activating the security cameras for now so that you can research the security bots. Exit this room now, research the Spider Splicer, and then kill him. Spider Splicer hearts can also be used as first aid kits, so you REALLY have no excuse for dying now. In the room behind you, there is a safe to hack, but for now, you are free to exit the Fighting McDonagh's Tavern.
Before exiting, you will be attacked by a Nitro Splicer and his pet security bot, so destroy them. At this point, I also unlocked Security Bot Research Level 2, which unlocks Tonic #13/53: Security Expert 2. This is a more efficient version of the first tonic and has a similar stacking effect to any other multi-tonic tonics. I personally decided to have a look around the basement and found a Big Daddy walking around. At this point, it's important to note that even if a Big Daddy is walking around with a Little Sister, DO NOT KILL HIM. Wait until he calls for the Little Sister from the Gatherer's Vent. Research both of them before killing the Big Daddy, and then deal with the Little Sister. Save her with . Do note that while this is a strange place for the Big Daddy to spawn, they can spawn anywhere within the level you are in, so be alert for any Big Daddies, and never attack them unless they are with a Little Sister. You will most likely find your third and final Little Sister for this level around Fontaine Fisheries after dealing with Jet Postal. Upon exiting the tavern, head into Jet Postal straight ahead from you.
Upon entering Jet Postal, kill the splicers, and from where you entered, turn left to find Audio Diary #37/122: Death Penalty in Rapture on a table. Now head through the main door of Jet Postal, and you will be jumped by the third and final Spider Splicer you have to photograph. Do so, and you will be free to head back to Peach Wilkins. Head back to his room by following the arrow, killing splicers on the way. Strangely, though, to the left of the Gene Bank, you will notice a tonic that wasn't there before on the ledge. Pick it up for Tonic #14/53: Wrench Lurker. This tonic increases wrench damage on attacks done stealthily (enemies that don't know you're there). You will also get jumped by a Spider Splicer with a lot of health on your way.
Upon reaching Peach Wilkins' room, knock on the door again to hear some more monologue. You will now also be able to pick up the Grenade Launcher if you didn't pick it up in the secret area earlier. When the door opens, you will notice a tonic buried in some ice to your left. Melt the ice with Incinerate, and you will find Tonic #15/53: Focused Hacker. This creates two less overload tiles in the hacking minigame and can be very useful if you haven't hit 50 hacks yet. You will now have to give up your weapons into the Pneumo Tube to your right, so do so. Upon entering the room while only armed with your wrench, camera, and Plasmids, you will be ambushed by Peach Wilkins. Just like Steinman, he really doesn't have that much more health than an ordinary splicer, so just keep hitting him with your wrench until he dies. Upon defeating him, you will unlock:
You will now be free to collect your weapons from the Pneumo Tube at the end of this room, so do so. Straight ahead of you will be your first Power to the People Station. These stations allow you to upgrade your weapons with attachments such as increased clip size or rate of fire. There are 2 upgrades per all 6 weapons, and there are 12 stations throughout the game, so you will be able to purchase every upgrade. That being said, feel free to choose whichever upgrade you wish at each of these stations. Use this station for Weapon Upgrade Station #1/12. For using your first Power to the People Station, you will unlock:
Turn left from this station, and use Incinerate on the ice covering the door to your left. Kill the splicers in here, and at the end of the room by the safe, you will find Audio Diary #38/122: Putting The Screws On. You can also hack the safe if you wish. Leave this room, and melt the ice with Incinerate covering the door on the other side of the room. You will encounter another apparition sequence, so after that's done, melt the ice at the end of the room, head through the next hallway, and move on to the Smuggler's Hideout.